THE OLIVE TREE

Bill Wilson is on record for having found a solution in 1960 for treating anxiety and depression

2013-04-10T03:40:00.001-07:00

Bill Wilson is on record for having found a solution in 1960 for treating anxiety and depression using vitamin B-3 therapy and worked tirelessly for eleven years begging for its inclusion into A.A. recovery circles. His desire was to help alcoholics stay recovered. This means he would have immediately brought this mineral replacement therapy that eliminates alcohol cravings forth without exception. Master of ceremonies, Andrew W. Saul, includes Bill Wilson as an inductee of the Orthomolecular Medicine Hall of Fame at the Hotel Vancouver, British Columbia, Canada, April 29, 2006 in his induction speech, “…To this day, selective history records A.A.’s 12-Step Program, but has forgotten, or deliberately purged, what Bill wanted to be A.A.’s 13th step – orthomolecular therapy with vitamin B3.”[Lee Brack1] In February 2009, Orthomolecular Medicine’s founder, Abram Hoffer and Bill Wilson’s good friend, clarified to me over the phone, “..yes, Lee, he wanted to share this information as an added step and talked about it all the time because he felt so strongly about nutrition…” Abram Hoffer passed away a few months later in May having lived healthy and happily for ninety one and a half years.

6 April 2013 Tuned-In Centre, Majuba Road, Redcar, TS10 5BJ

2013-04-01T08:03:00.001-07:00

Event	North-West District of Cocaine Anonymous welcomes you to... Reaching Out in Redcar UNITY Day
Time	Saturday 11:30am Start
Address	Tuned-In Centre, Majuba Road, Redcar, TS10 5BJ
Additional Notes	Speakers; Cameron F (Canada) Will B (Spain) Danielle (Cheshire)
Information	TICKETS £5 (or donation). Refreshments provided. Click here to download flyer & contact info.

Understand the inherently peaceful presence of Awareness the art of Living in the NOW

2013-03-31T08:14:00.001-07:00

Understand the inherently peaceful presence of Awareness the art of Living in the NOW, and see that this peace is not dependent upon the condition of the mind, body or world, just as a screen is not dependent on the quality of the words or images that appear on it.

The addicted brain is distinctly different from the nonaddicted brain, as manifested by changes in brain metabolic activity, receptor availability, gene expression, and responsiveness to environmental cues

2013-03-29T00:00:00.001-07:00

There are many biological factors that are involved with the addicted brain. "The addicted brain is distinctly different from the nonaddicted brain, as manifested by changes in brain metabolic activity, receptor availability, gene expression, and responsiveness to environmental cues" (2) In the brain, there are many changes that take place when drugs enter a person's blood stream. The pathway in the brain that the drugs take is first to the ventral tegmentum to the nucleus accumbens, and the drugs also go to the limbic system and the orbitofrontal cortex, which is called the mesolimbic reward system. The activation of this reward system seems to be the common element in what hooks drug users on drugs (2).

Drugs seem to cause surges in dopamine neurotransmitters and other pleasure brain messengers. However, the brain quickly adapts and these circuits desensitize, which allows for withdrawal symptoms to occur (3). Drug addiction works on some of the same neurobiological mechanisms that aid in learning and memories (3). "This new view of dopamine as an aid to learning rather than a pleasure mediator may help explain why many addictive drugs, which unleash massive surges of the neurotransmitter in the brain, can drive continued use without producing pleasure-as when cocaine addicts continue to take hits long after the euphoric effects of the drug have worn off or when smokers smoke after cigarettes become distasteful." (4)

Since memory and pleasure zones are intertwined in the brain, many researchers have been using psychological approaches to stop drug use. Many rehabilitation centers have used classical conditioning to rehabilitate drug addicts. They combine exposure to drugs combined with cognitive scripts, like statements how drugs have destroyed a person's life or what can be accomplished without using drugs, according to DeLetis (5). By using classical conditioning, the drugs addicts pair the drugs with negative connotations and properties. "Adverse withdrawal symptoms can function as an instrumental negative reinforcer and can be linked to the opponent process theory of motivation." (6) However, drug addicts may relapse and start using again because of many environmental "cues", which are external forces that are associated with drug use in their lives. When the drugs addicts see these cues, their brain circuitry, especially the orbitofrontal cortex become hyperactive and causes these people to start craving drugs again (2). No matter how successful the rehabilitation treatment is, once those "cues" are around, the drug addicts remember how pleasurable the drugs felt and relapse into drug abuse again.

Through all of the research done about drug addiction and its affects on the brain, one can see how drug addiction is considered a brain disease. Drug addiction is a disabling disease and can ruin a person's life. By taking drugs, a person's brain becomes "rewired" to tolerate high amounts of dopamine neurotransmitters, but once those high amounts of dopamine cease to exist, the person experiences withdrawal symptoms. However, there are ways drug addicts can control their drug intake by using classical conditioning techniques, which allows them to associate drugs with negative attributes.

Bill Wilson is on record for having found a solution in 1960 for treating anxiety and depression using vitamin B-3 therapy and worked tirelessly for eleven years begging for its inclusion into A.A. recovery circles.

2013-03-27T15:42:00.001-07:00

The Serotonin Support Group (SSG)

Is a mutual support group for people who suffer from low Serotonin levels, wishing to participate in a support group that uses as one method a vitamin supplement as a method of replacement or addition to a diet to help the sufferer.The historical basis of this form of nutritional treatment was discovered and researched by Bill Wilson of Alcoholics Anonymous and it is to promote this Legacy to persons who suffer from low serotonin uptake and depression that the Group was formed.Bill Wilson wished to add a step to the 12 he had produced for AA. We struggle to make that possible and fulfill his promise. Without detracting from the message of recovery in the twelve steps of Alcoholics Anonymous. If alcoholics and addictive abusers of other drugs have specific chemical imbalances in the brain, and if these imbalances turn out to be reliable enough and measurable enough in sufficiently large numbers of human addicts, it is natural to wonder whether, eventually, science can find a way to correct them.

Some sort of neurotransmitter cocktail, maybe.

Or just possibly... a pill?

Bill Wilson is on record for having found a solution in 1960 for treating anxiety and depression using vitamin B-3 therapy and worked tirelessly for eleven years begging for its inclusion into A.A. recovery circles. His desire was to help alcoholics stay recovered. This means he would have immediately brought this mineral replacement therapy that eliminates alcohol cravings forth without exception. Andrew W. Saul, includes Bill Wilson as an inductee of the Orthomolecular Medicine Hall of Fame at the Hotel Vancouver, British Columbia, Canada, April 29, 2006 in his induction speech, “…To this day, selective history records A.A.’s 12-Step Program, but has forgotten, or deliberately purged, what Bill wanted to be A.A.’s 13th step – orthomolecular therapy with vitamin B3.”[Lee Brack1] In February 2009, Orthomolecular Medicine’s founder, Abram Hoffer and Bill Wilson’s good friend, clarified to me over the phone, “..yes, Lee, he wanted to share this information as an added step and talked about it all the time because he felt so strongly about nutrition…” Abram Hoffer passed away a few months later in May having lived healthy and happily for ninety one and a half years.

The results strongly suggest that the mechanism of depression after alcohol drinking may be related to serotonin.

2013-03-27T15:39:00.001-07:00

We examined tryptophan and serotonin (5-hydroxytryptamine) levels in the blood after consumption of alcohol. Forty-five minutes after drinking, whole blood serotonin concentration was significantly reduced, whereas no changes were observed in tryptophan level. The diurnal rhythm of 5-HT in subjects who the day before had drunk alcohol was quite different from the control group, but very similar to that of patients with depression. The results strongly suggest that the mechanism of depression after alcohol drinking may be related to serotonin.

The important thing with serotonin, is to keep it at steady levels.

2013-03-27T15:36:00.001-07:00

The important thing with serotonin, is to keep it at steady levels. The medicines that raise the level of serotonin in the brain do so by slowing the reabsorbtion of serotonin. The alcohol increases the availible serotonin for a bit and then it drops off quickly, leaving the depressed person feeling worse, and they tend to not take the medicine correctly when they feel badly or are drunk. High serotonin levels do not mean somebody will feel happy or good, It makes it more likely that they won't feel realy bad.

Ms Sandiford to be executed for drug trafficking.

2013-01-22T02:26:00.001-08:00

Lindsay Sandiford was arrested in May last year after she tried to enter the Indonesian holiday island with illegal drugs worth £1.6 million hidden in her suitcase.

Local prosecutors had called for the 56-year-old housewife to be jailed for 15 years. But today there were gasps in the Bali courtroom when a panel of judges announced Ms Sandiford would be executed for drug trafficking.

As the shock verdict was announced, Ms Sandiford, from Gloucestershire, slumped back in her chair in tears before hiding her face with a brown sarong as she was led out of the courtroom.

Marbella Forest Fire

2012-09-02T12:00:00.001-07:00

OwnFone: A Custom-Printed Phone Perfect for Seniors and Kids

2012-08-27T03:22:00.001-07:00

Some people need all the latest apps and features available on their smartphone so they can be connected 24/7, while others just want to make a phone call. For the connected crowd, read all the latest reviews onMashable. For the others, check out the OwnFone.

It’s designed to call only the people you want to reach most frequently. In fact, it can only hold 12 contacts. There are no keys or buttons to program. Instead you let OwnFone know who you want to add, and they program and send you a custom-printed phone, about the size of a credit card.

If you lose it, they just print you a new one. You do need to call OwnFone support if you need to change someone’s number, or add a contact.

OwnFone says it plans to come out with a phone that can be customized in braille in the near future. Right now OwnFone is only available in the UK.

Check out the video above for more details and let us know what you think of a printed, pre-programmed cell phone.

Estepona Wild Fires rage on a 2km front

2012-08-25T17:33:00.001-07:00

Police and Ambulances hurried to evacuate as wild fires quickly spread our reporter on the scene photographer the devastation

Estepona on Fire

2012-08-25T17:21:00.001-07:00

We had a tiny little fire today, which they put out.

Then an hour later, it restarted, and spread along 2 Klm of the coast.

It was horrible seeing old people being run out of their homes, and carried through the smoke by police and ambulances.

The pictures really doesn,t do show bad it really was.many houses have gone

During experiments on the axons of the Woods Hole squid (loligo pealei), we tested our cockroach leg stimulus protocol on the squid's chromatophores.

2012-08-25T04:02:00.001-07:00

The results were both interesting and beautiful. The video is a view through an 8x microscope zoomed in on the dorsal side of the caudal fin of the squid. We used a suction electrode to stimulate the fin nerve. Chromatophores are pigmeted cells that come in 3 colors: Brown, Red, and Yellow. Each chromatophore is lined with up to 16 muscles that contract to reveal their color.

Paloma T. Gonzalez-Bellido of Roger Hanlon's Lab in the Marine Resource Center of the Marine Biological Labs helped us with the preparation. You can read their latest paper at:http://rspb.royalsocietypublishing.org/content/early/2012/08/13/rspb.2012.1374

London's secret music venue and their livestream act

2012-08-13T16:26:00.001-07:00

With an invite-only door policy and super secret location, Boiler Room is London's most exclusive music venue. But elitism isn't the premise for its clandestine nature—in fact, anyone with an Internet connection can easily join in the fun. Using a simple webcam, the crew behind Boiler Room livestreams each set for the world to see free of charge, and each month more than a million viewers tune in to see performances by artists like James Blake, The xx, Roots Manuva, Neon Indian, Juan Maclean and more.

We recently chilled out to the smooth sounds of Brooklyn's How To Dress Well before rocking out to revered musician Matthew Dear, who brought down the house with an intense 40-minute DJ set. Keep an eye out for our interview with Dear, but for now you can get a little more insight into the underground music scene's most talked about livestream show by checking out our interview with assistant musical programmer and Boiler Room host Nic Tasker.

How important is it for Boiler Room to remain secret, at least in its location?

That is quite an important aspect of it, purely because it means when you do shows you don't get a lot of groupies, pretty much everyone in the room is either a friend of ours or one of the artist's. It helps to create a more relaxed atmosphere for the artist and I think they feel less pressure. They're also just able to chill out and be themselves more rather than having people being like, "Hi can I get your autograph?" If the artists are relaxed usually you get the best music.

It seems like there is more interaction among the crowd than at a typical venue, is that intentional?

It's definitely a social place. All the people that come down, most of them we know and they're all our friends. So they come down, hang, have a drink and just chill out, basically. From our very set-up, we do it with a webcam, we're not a highly professional organization but I think that's kind of the charm of it. The main thing is people come down with the right attitude.

How much of the show is prescribed?

I guess that depends on the artist. We never say anything. Literally, whatever they want to do—we're kind of the platform for them to do whatever they want, so if Matthew Dear wants to come and play an hour of noise with no beats, he can do that. That's fine with us, and I think that's why artists like coming to play for us. We're not like a club where you have to make people dance, we don't give a shit if people dance. It's nice if they do and it makes it more fun, but some nights you just get people appreciating the music, which is equally fun.

Is there a particular kind of artist you guys look for and ask to come perform?

No, not particularly, it's just whatever we're feeling. Thristian [Boiler Room's co-founder] has the main say on musical direction, but it's a massive team effort. In London there's five of us, New York there's two, LA there's one and Berlin there's two.

Tonight you had different set-ups for each artist, do you tailor their positioning in the room to their style?

It definitely depends on the act and what kind of music they do. With live bands we found what works nicely is having them opposite each other because it's like they're in rehearsal, like they're just jamming. Which is again trying to give them that chilled out feel that they're just at home jamming and there happens to be a camera there. For some of our shows we've had over 100,000 viewers. When you think of those numbers it's quite scary, but when you're in the room and it's all friends it creates that vibe that people don't mind. You can imagine if you had all those people in front of you it would be a very different situation.

Have you ever thought of Boiler Room as an East London version of Soul Train?

It's never crossed my mind like that, but I can see why you think that. I like to think of us as the new music broadcaster, kind of the new MTV, but obviously we operate in the underground scene mainly. But I like to think that what we do is as revolutionary as what they were doing. We're always growing into something new.

What's up next for Boiler Room?

We have had visual people in doing 3D mapping, and that's something we're looking forward to progressing—doing more with the visuals. We've got the upstairs as well, we're starting to do breakfast shows with some high profile DJs, we're going to be doing that regularly. Each will have an individual format. The next step is progressing the US shows, we're alternating weekly between New York and LA, so the next step is to take Boiler Room to America

Breaking Free of the Co-dependency Trap presents a groundbreaking developmental road map to guide readers away from their co-dependent behaviors and toward a life of wholeness and fulfillment.

2012-08-13T02:08:00.001-07:00

Breaking Free of the Co-dependency Trap presents a groundbreaking developmental road map to guide readers away from their co-dependent behaviors and toward a life of wholeness and fulfillment.UK Citizens

This is the book that offers a different perspective on codependency and is strongly recommended by Dream Warrior Recovery as part of a solution based recovery. This bestselling book, now in a revised edition, radically challenges the prevailing medical definition of co-dependency as a permanent, progressive, and incurable addiction. Rather, the authors identify it as the result of developmental traumas that interfered with the infant-parent bonding relationship during the first year of life.US Citizens

Drawing on decades of clinical experience, Barry and Janae Weinhold correlate the developmental causes of co-dependency with relationship problems later in life, such as establishing and maintaining boundaries, clinging and dependent behaviors, people pleasing, and difficulty achieving success in the world. Then they focus on healing co-dependency, providing compelling case histories and practical activities to help readers heal early trauma and transform themselves and their primary relationships.

Pigs worship God of Materialism

2012-08-05T19:57:00.001-07:00

If ever there was a god to prevent you from worshiping material things, it would be this one.

The hideous pig-like thing is the masterpiece by Chinese artist Chen Wenling called God Of Materialism.

Ugly pig with green eye darting at thier master

Looking chuffed, the huge greedy pig has minions of other tiny, and just as unattractive and scary, pigs worshiping in awe at its heels.

The group stare up at their master, adorned with a plethora of jewels and necklaces representing the grotesque love of material things.

The sculpture, which looks like a bad dream, can be found at the Asia Art Centre in Beijing.

And if you're brave enough to go and see it, it will be there till October 18th 2008.

Brad Pitt is reportedly utilising his free time to plan his wedding with Angelina Jolie.

2012-08-05T02:41:00.001-07:00

The 48-year-old has taken charge of preparations for the wedding that is expected to take place end of September. He has flown in a team of builders to renovate the home he shares with Jolie in southern France.

"Angelina isn`t so bothered about when they tie the knot, it`s Brad who is piling on the pressure," a website has quoted a source as saying.

"He wants the main house to be finished when the event takes place, even though the close friends and relatives who are invited aren`t the types to care. He wants everything to be absolutely perfect," the source added.

yellow jacket stun gun case for iphone

2012-08-04T03:56:00.001-07:00

yellow jacket is a case that transforms the iPhone 4 & 4S into that 650,000-volt stun gun you've always needed.

scheduled to hit the US market in fall 2012 the case is advertised as being able to
easily stop an aggressive male attacker, and ready for use in less than two seconds.
its designer seth froom, a former military policeman came up with the product after
being robbed in his home at gunpoint.

what is the demand for such a hostile product you might ask? well, yellow jacket
has managed to receive over 100,000 USD worth of backing on the crowd-funding
website indiegogo which means that there must be quite a few people out there
who feel the need to transform their phone into a weapon.

detail of the stun gun nodes

the iPhone's designers could never have conceived half of the the weird and wonderful accessories
that have been designed for use with the iPhone since its launch, but even in the name of self defense
a stun gun seems a bit much, doesn't it?

Now You Can Buy a $250,000 Nail Polish

2012-08-02T17:39:00.001-07:00

Remember that time when everyone got all freaked out about thatsnakeskin pedicure that cost $300? Well, get ready to completely lose it, because we just got a press release for the “most expensive nail polish in the world.”

That title was previously held by Models Own, which produced a $130,000 bottle (featuring a 24-carat gold, diamond-encrusted lid) back in 2010. However, the self-professed “king of black diamonds,” Azature, has doubled that figure. A bottle of black nail polish containing a whopping 267 carats of black diamonds in the actual polish will go for $250,000. Yikes. You won’t be able to just walk into Duane Reade and buy this sucker, however–only one bottle of the stuff will be produced.

For those of us who can’t afford a quarter of a million dollars for a manicure, Azature is offering a $25 version (see, now doesn’t $25 nail polish sound downright cheap in comparison?) containing one measly black diamond. You’ll be able to pick it up in LA at Fred Segal starting this month.

Estepona Town Hall sacks 176 municipal workers

2012-08-02T16:50:00.001-07:00

The news was given on Wednesday by the Councillor for Personnel, Pilar Fernández-Figares Estepona Town Hall has sacked 176 municipal workers. The PP Councillor for Personnel, Pilar Fernández-Figares, announced on Wednesday that the 176 workers are victims of the ERE Employment Regulation which the Town Hall put forward in June. The workers will be compensated with 2.5 million € and they will be given their ‘finiquito payments of 408,000 € between them. Pilar Fernández-Figares said one they were sacked the Town Hall will start to work on a new ‘training program for the reinsertion of the sacked workers’.

BMW to sell luxury cars for less online

2012-07-29T11:23:00.001-07:00

The BMW i3 concept car at the 2012 Detroit Auto Show in January. (John T. Greilick / Detroit News)

BMW will sell cars over the Web for the first time as the world's largest maker of luxury vehicles seeks an inexpensive way to reach more buyers to recoup spending on its electric models.

A direct online sales platform for BMW's new I sub-brand will be unique in an industry where, outside of small-scale experiments, competitors leave Internet orders for cars to dealers. BMW's range of strategies for the models, including a roaming sales force backing a limited showroom network, reflects the challenge carmakers face as low-emission vehicles trickle into dealerships to sluggish demand after years of development.

"There is considerable risk in BMW's approach of promoting the I brand so prominently," said Stefan Bratzel, director of the Center of Automotive Management at the University of Applied Science in Bergisch Gladbach, Germany. "There is the image risk, if they don't succeed as quickly as expected, and then there's the main risk of costs, which can only be countered with high deliveries."

BMW opened the I models' first showroom Tuesday in London, although only prototype cars and informational materials will be displayed at first because the vehicles themselves won't go on sale before next year. BMW is spending about $3 billion developing the i3 battery-powered city car and i8 plug-in hybrid supercar, according to an estimate by Frost & Sullivan. Industry sales of electric cars last year, at 43,000 vehicles, were only 57 percent of the 75,000 deliveries predicted by Sarwant Singh, a London-based automotive partner at the consulting company.

Starting prices posted

The four-seat i3, scheduled to reach the market in late 2013, will be priced at about 40,000 euros ($48,500), Bratzel estimated. That compares with a 23,850-euro starting price ($29,388) in Germany for the 1-Series, the cheapest BMW-brand car. The i8, targeted for sale in 2014, will cost more than 100,000 euros ($123,221), according to Ian Robertson, BMW's sales chief.

Details of how I-model buyers, the website and dealerships will interact are "still in the planning process" and will be communicated later, Linda Croissant, a spokeswoman at Munich- based BMW, said last week. Sales will be focused on the world's major urban areas, she said.

The online sales option is aimed at a generation of drivers used to making daily purchases over the Internet, and will be an extension of the car configuration that most automakers offer customers to view models with desired options such as interior colors, seat materials and roof styles.

Test drives not an option

The Internet platform may take a while to catch on because "many customers will still want to go somewhere to look at and drive the vehicle before buying," said Ian Fletcher, an auto analyst in London at research company IHS Global Insight.

"With new technologies, there may be even greater skepticism about buying a car over the Internet, as in many cases you'll have to win the confidence of customers that it works and there is support for them," Fletcher said in an email.

The setup may help BMW reduce expenses: Internet sales require less than half the cost of distributing through a dealership, according to Ferdinand Dudenhoeffer of the Center Automotive Research at the University of Duisburg-Essen in Germany. That allows online car prices to be 5 percent to 7 percent less than showroom tags.

Still, BMW sees standard dealerships as "the backbone of what we are doing in the interface with the customer" for the I models, Robertson said in June at a press presentation at the sub-brand's Park Lane showroom in London.

Dealer selection criteria

Outlets will be restricted to dealers with high BMW-brand sales volume who have floor space as well as capacity to work with I models' powering technology and carbon-fiber body material, Robertson said. The carmaker has chosen 45 of its approximately 200 dealers in Germany to sell the i3 and i8, a ratio that will probably be similar elsewhere, he said.

Dealers will be designated as agents for the I models, which provides an "advantage" by keeping the vehicles on the carmaker's books, the association of BMW distributors in Germany said in an email.

Electric vehicles' disadvantages versus conventional cars include costly battery packs, limited ranges and the time needed to recharge. Consumer reception to models like the Nissan Motor Co.'s Leaf and General Motors Co.'s Chevrolet Volt has been tepid.

"Currently available electric cars have a limited market success because they are a big compromise," said Arndt Ellinghorst, a London-based analyst at Credit Suisse AG. "Customers are not willing to compromise and spend a lot of money."

Carbon fiber bodies lighter

BMW Chief Executive Officer Norbert Reithofer started Project I at the end of 2007 as tighter emissions regulations threatened the viability of sporty sedans. BMW chose to create all-new vehicles that use expensive carbon fiber for a lighter body to make up for the weight of the battery system.

The approach contrasts with a decision by Daimler AG's Mercedes-Benz Cars division to convert existing models, such as the van-like B-Class or two-seat Smart, to electric power.

To make its electric vehicles more attractive, Stuttgart, Germany-based Daimler's Smart brand offers to lease the battery separately from the car. The automaker has a target of selling more than 10,000 of the models next year, with a starting price of 18,910 euros plus monthly battery rental at 65 euros.

The I models' new technology poses risks for BMW, "but they have no choice if they want to keep their premium and image as an innovation leader," Ellinghorst said.

The i3 and i8 will probably be among BMW's lowest-selling models through 2024, alongside the existing Z4 roadster, according to IHS estimates. In 2014, the first full year of production, BMW will probably deliver 31,380 i3s, compared with 564,760 of the best-selling 3-Series model and 18,101 Z4s, a study by the research company shows.

BMW's stance is that the models should produce earnings from the start, sales chief Robertson said.

"We clearly, as a company, go into any product launch with the view of making profit, which is no different with the I brand," Robertson said. "This is a car line just as every other car line, and we intend to make profit from Day 1."

Bankers face the prospect of jail as Serious Fraud Office launches criminal probe into interest-rate fixing at Barclays

2012-07-06T08:34:00.001-07:00

Hearing: Former chief executive Bob Diamond left Barclays over the matter, before appearing before MPs this week

A criminal investigation has been launched into alleged rigging of the Libor rate within the banking industry, the Serious Fraud Office (SFO) confirmed today.

SFO director David Green QC formally accepted the Libor issue for investigation after Barclays was fined by the Financial Services Authority (FSA) last week for manipulating the key interbank lending rate which affects mortgages and loans.

The claims ultimately led to the resignation of Barclays boss Bob Diamond and have become the focal point of a fierce political debate over ethics in the banking sector.

The investigation could ultimately lead to criminal prosecutions and bankers facing charges in court.

The SFO's update came after it revealed earlier this week that it had been working closely with the FSA during its investigation and would consider the potential for criminal prosecutions.

The Government department, which is responsible for investigating and prosecuting serious and complex fraud, said on Monday the issues surrounding Libor were "complex" and that assessing the evidence would take time.

Under fire: Barclays former chairman Marcus Agius (right) with former CEO Bob Diamond (centre), and former chief executive John Varley (left)

As the SFO prepares its investigation, Labour leader Ed Miliband continued to push for an independent inquiry into the banking scandal despite MPs rejecting the demands.

The Labour leader said that while the party would cooperate with a parliamentary investigation, its remit was too "narrow" and a judge-led probe was still needed.

Mr Miliband also defended the conduct of Ed Balls after the shadow chancellor engaged in a bitter war of words with his opposite number George Osborne in the Commons.

Diabetes drug makes brain cells grow

2012-07-05T21:53:00.001-07:00

The widely used diabetes drug metformin comes with a rather unexpected and alluring side effect: it encourages the growth of new neurons in the brain. The study reported in the July 6th issue of Cell Stem Cell, a Cell Press publication, also finds that those neural effects of the drug also make mice smarter. See Also: Health & Medicine Brain Tumor Stem Cells Nervous System Mind & Brain Brain Injury Intelligence Neuroscience Strange Science Reference Neural development Stem cell treatments Diabetes mellitus type 2 Embryonic stem cell The discovery is an important step toward therapies that aim to repair the brain not by introducing new stem cells but rather by spurring those that are already present into action, says the study's lead author Freda Miller of the University of Toronto-affiliated Hospital for Sick Children. The fact that it's a drug that is so widely used and so safe makes the news all that much better. Earlier work by Miller's team highlighted a pathway known as aPKC-CBP for its essential role in telling neural stem cells where and when to differentiate into mature neurons. As it happened, others had found before them that the same pathway is important for the metabolic effects of the drug metformin, but in liver cells. "We put two and two together," Miller says. If metformin activates the CBP pathway in the liver, they thought, maybe it could also do that in neural stem cells of the brain to encourage brain repair. The new evidence lends support to that promising idea in both mouse brains and human cells. Mice taking metformin not only showed an increase in the birth of new neurons, but they were also better able to learn the location of a hidden platform in a standard maze test of spatial learning. While it remains to be seen whether the very popular diabetes drug might already be serving as a brain booster for those who are now taking it, there are already some early hints that it may have cognitive benefits for people with Alzheimer's disease. It had been thought those improvements were the result of better diabetes control, Miller says, but it now appears that metformin may improve Alzheimer's symptoms by enhancing brain repair. Miller says they now hope to test whether metformin might help repair the brains of those who have suffered brain injury due to trauma or radiation therapies for cancer.

Spanish Tourism Industry Prepares for Difficult Summer

2012-07-05T13:13:00.001-07:00

Spain's tourism industry is bracing itself for a painful slowdown in bookings this summer, driven by a steep decline in local tourism, according to the country's leading hotel association. Reservations by Spanish vacationers for the month of July are 30% lower than last year, amid persistently high unemployment and a protracted economic recession, said Juan Molas, president of the Spanish Confederation of Hotels and Tourist Accommodations. An influx of visitors from Russia and other countries in Eastern Europe has compensated somewhat for the decline in local tourism, but weak local demand is expected to weigh on an industry that accounts for about 11% of Spain's annual economic output. Hotel owners are concerned that the government may raise the industry's value-added tax to 18% from the current 8%, in a bid to reduce its yawning budget deficit, making Spain less attractive to foreign tourists compared with other less expensive destinations "If the VAT rises to 18%, it will be absolutely catastrophic for the sector," Mr. Molas said at an event Thursday in Madrid. Spain's government is working to secure €100 billion ($126 billion) in aid for its struggling banking sector from the European Union and plans to meet with EU officials next week to discuss new measures to improve its public finances. Prime Minister Mariano Rajoy has already implemented €45 billion in austerity measures, but weak tax revenue threatens to undermine his administration's goal of trimming its shortfall this year to 5.3% of gross domestic product from 8.9% last year. Sentiment in the hospitality industry is at its lowest level since 2009, according to an index developed by the hotel association and consulting firm PwC. Based on a survey of hotel firms, 57% of operators expect international tourism will hold steady this year, while 76% expect domestic tourism to decline. "The parts of the country that will suffer the most are those that cater to national tourists," Mr. Molas said.

Holidaymakers in Spain this summer are facing a surprise new airport tax imposed by the Spanish government

2012-07-05T09:20:00.001-07:00

Holidaymakers in Spain this summer are facing a surprise new airport tax imposed by the Spanish government as it tries to balance its books. Some airlines are passing the new departure tax on to passengers, even if they booked their flights months ago. Some passengers have received emails telling them either to pay an extra charge of up to seven euros (£6) per person - or to cancel their flights. Other airlines are deciding whether to absorb the cost themselves. The budget airline Ryanair said Spain's 2012 budget, passed into law at the end of June, obliged airlines to pay increased taxes. Spain is implementing drastic measures to try to slash its budget deficit to 5.3% from 8.5% in 2011. It has been promised bailout funds of up to 100bn euros for its banks, but wants to avoid a full state bailout. Retrospective The European travel agents' association ECTAA said the amount of the extra levy varied depending on which airport people used. It said the average rise in the tax was 18.9%, but at some of the larger airports it would almost double. For instance, at Madrid-Barajas the tax would rise from 6.95 euros to 14.44, while at Barcelona's El Prat airport it would rise from 6.12 euros to 13.44. Ryanair said it would pass the cost on to passengers, even those who had already paid in full for their flights, because the tax applied "retrospectively to customers who booked flights before 2 July 2012 and are travelling from 1 July onwards". It said for bookings made on or after 2 July, the increased tax would have been included in the price. The Spanish low-cost airline Vueling is also passing on the cost. It sent emails to passengers giving them seven days to cancel their flight, or the extra payment would be debited automatically from the card they used to book. British Airways and Iberia told the BBC they had not yet decided whether to pass on the cost or absorb it. ECTAA said in a statement it was "dismayed" by the rise, which was imposed "without proper consultation of airport users nor appropriate implementation time". It said travel agents faced a "technical and financial nightmare to recover the extra charge".