Medscape Psychiatry & Mental Health Headlines

Novel First-in-Class Drug Promising in Early ADHD Study

Tue, 22 Sep 2026 08:58:21 EDT

A novel orexin-2 receptor agonist showed ‘clinically meaningful’ outcomes in adult ADHD in a new phase 1B study, making it one of the first of its class to show such a signal.

What 95,000 Wrist Trackers Revealed About Sleep

Tue, 22 Sep 2026 06:14:36 EDT

Sleep duration and stages, including REM and deep sleep, were associated with risk for multiple diseases, with a sleep duration of 6-8 hours showing the greatest benefit.

Adult ADHD: Does Age at Diagnosis Affect Clinical Profile?

Tue, 22 Sep 2026 05:07:49 EDT

Adults diagnosed with ADHD later in life have fewer comorbidities, less functional impairment, and milder genetic profile than those diagnosed during childhood or adolescence.

Partner Similarity May Amplify Psych Illness Heritability

Mon, 21 Sep 2026 08:56:58 EDT

Individuals with psychiatric disorders, especially schizophrenia, tend to partner with each other, which may increase the prevalence and heritability of the disorders, new research shows.

Caplyta Meets Main Goal Of Bipolar Mania Study

Mon, 21 Sep 2026 08:50:07 EDT

Johnson & Johnson said on Monday its experimental use of Caplyta for bipolar mania met the ⁠main goal of a late-stage study, bringing the drug a step closer to expanding...

Mental Health Review Rejects 'Snowflake Generation' Tag

Mon, 21 Sep 2026 07:21:44 EDT

Review author Peter Fonagy says today's young people face real mental health struggles, not a ‘snowflake generation’ myth.

Autism Linked to 14-Year Shorter Life Expectancy in the US

Mon, 21 Sep 2026 05:05:29 EDT

Autism spectrum disorder in the US is associated with a 14-year shorter life expectancy compared to the general population, a large cross-sectional study shows.

Kennedy Names New Chair for US Autism Advisory Panel

Fri, 18 Sep 2026 15:41:25 EDT

US Health Secretary Robert F. Kennedy Jr. named an ally, Dr. John Gaitanis, to lead a key federal advisory panel on autism on Friday, replacing a chair who had just steered...

GLP-1s Are Treating a Diagnosis. Who’s Treating the Patient?

Fri, 18 Sep 2026 12:52:10 EDT

Without nutrition and eating disorder support, clinicians prescribing GLP-1s may miss undernutrition, muscle loss, and harmful restriction.

Self-Silencing Linked to Depression in Long-Term HIV

Fri, 18 Sep 2026 09:11:49 EDT

Women living with HIV for 15 years or longer show heightened depression and self-silencing during the COVID pandemic, with the link to depression being stronger among those with prior COVID.

Kids With Congenital Droopy Eyelids More Likely to Have ADHD

Fri, 18 Sep 2026 08:46:29 EDT

A new study finds nearly 1 in 5 children with congenital ptosis — a condition causing drooping eyelids — are diagnosed with ADHD, a rate far above that seen in the general pediatric population.

Hot Suicidal Ideation in MDD Tied to Reduced Brain Volumes

Fri, 18 Sep 2026 08:00:00 EDT

Hot or affectively driven suicidal ideation is associated with reduced thalamo-pallidal volumes in patients with major depressive disorder, whereas deliberate or cold ideation is not.

ADHD, Autism in IBD: Different Disease Course?

Fri, 18 Sep 2026 08:00:00 EDT

Paediatric and young patients with IBD and ADHD or autism vs IBD alone show no difference in the risk for severe disease at 1 year but a lower risk for hospitalisation with more hospital contacts.

After 50 Years of Failed Attempts, Is a Drug Vaccine Close?

Fri, 18 Sep 2026 05:16:43 EDT

Researchers are working on vaccines and monoclonal antibodies to prevent fentanyl overdose. After decades of failed attempts to create a drug vaccine, is success finally within reach?

Nurse-Led Program Reduces Death Anxiety in Breast Cancer

Fri, 18 Sep 2026 04:10:33 EDT

A structured nurse-led support program combining in-person and virtual sessions reduces death anxiety among women with breast cancer undergoing hormonal therapy, a study reports.

Is AD Transmissible? The Evidence for ‘Iatrogenic’ Disease

Fri, 18 Sep 2026 04:08:05 EDT

Evidence for medically transmitted amyloid pathology is mounting, but whether Alzheimer’s disease itself can be transmitted — and what it means for patients — remains unsettled.

Spanish Experts Expand Care After Perinatal Loss

Fri, 18 Sep 2026 04:00:21 EDT

Spanish neonatologists say memory boxes, cooling cradles, and follow-up care can help families navigate perinatal grief after the loss of a baby.

What Extreme Athletes Teach Us About Sleep Deprivation

Thu, 17 Sep 2026 16:51:28 EDT

What can a 1000-mile race teach MDs about sleep? Dr Alison Kole shares sleep deprivation insights from ultramarathon racing and gives practical tips for exhausted patients.

Depression Drug Trials Paused Over Side-Effect Concerns

Thu, 17 Sep 2026 16:37:31 EDT

Xenon Pharmaceuticals on Thursday said it has temporarily paused enrolling new patients in clinical studies testing ⁠its experimental drug for major and bipolar depression,...

Cognitive Screening in MS: The Digital Advantage

Thu, 17 Sep 2026 10:31:11 EDT

Dr Elizabeth Gromisch explores digital cognitive screening in multiple sclerosis, from its role in care to clinical integration and emerging options.