Nature Neuroscience provides the international neuroscience community with a highly visible forum in which the most exciting developments in all areas of neuroscience can be communicated to a broad readership. A lively front half, including News & Views, Reviews, Perspectives and editorials, helps place the primary research in context, providing readers with a broad perspective on the entire field. Nature Neuroscience aims to provide readers with authoritative, accessible and timely information on the most important advances in understanding the nervous system. Areas covered include molecular, cellular, systems, behavioral, cognitive and computational studies. http://feeds.nature.com/neuro/rss/current Nature Publishing Group en © 2026 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Nature Neuroscience © 2026 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. permissions@nature.com https://www.nature.com/uploads/product/neuro/rss.gif http://feeds.nature.com/neuro/rss/current https://www.nature.com/articles/s41593-026-02258-4 Nature Neuroscience, Published online: 30 April 2026; doi:10.1038/s41593-026-02258-4

High-density single-neuron recordings in patients with epilepsy revealed interictal discharges are generated by structured laminar circuits. These circuits overlapped with cognitive circuits and could predict discharges up to 1 s in advance.]]> Alexander B. SilvaSiddharth A. MaratheQuinn R. GreiciusDuo XuShailee JainJason E. ChungXiaofang YangAnkit N. KhambhatiMatthew K. LeonardJonathan K. KleenEdward F. Chang doi:10.1038/s41593-026-02258-4 Nature Neuroscience, Published online: 2026-04-30; | doi:10.1038/s41593-026-02258-4 2026-04-30 Nature Neuroscience 10.1038/s41593-026-02258-4 https://www.nature.com/articles/s41593-026-02258-4 https://www.nature.com/articles/s41593-026-02263-7 Nature Neuroscience, Published online: 30 April 2026; doi:10.1038/s41593-026-02263-7

The authors identify glucose-derived conversion of citrate to acetyl-CoA upstream of histone acetylation as modulating the regional dynamics of oligodendrocyte progenitors, with extranuclear acetyl-CoA from other sources being used for myelination.]]> Sami SaumaStephanie StranskyIpek SelcenSimone SidoliRinat AbzalimovYe HePatrizia Casaccia doi:10.1038/s41593-026-02263-7 Nature Neuroscience, Published online: 2026-04-30; | doi:10.1038/s41593-026-02263-7 2026-04-30 Nature Neuroscience 10.1038/s41593-026-02263-7 https://www.nature.com/articles/s41593-026-02263-7 https://www.nature.com/articles/s41593-026-02280-6 Nature Neuroscience, Published online: 29 April 2026; doi:10.1038/s41593-026-02280-6

How the brain organizes the retrieval of old and new memories remains unknown. Kim et al. identify a septo−entorhinal GABAergic pathway that controls flexible switching between episodic memories during memory retrieval to enable memory updating.]]> Mujun KimBoin SuhSunhoi SoJung Wook ChoiJaemin HwangJuhee ParkJin-Hee Han doi:10.1038/s41593-026-02280-6 Nature Neuroscience, Published online: 2026-04-29; | doi:10.1038/s41593-026-02280-6 2026-04-29 Nature Neuroscience 10.1038/s41593-026-02280-6 https://www.nature.com/articles/s41593-026-02280-6 https://www.nature.com/articles/s41593-026-02231-1 Nature Neuroscience, Published online: 28 April 2026; doi:10.1038/s41593-026-02231-1

Related memories are sometimes encoded in overlapping neurons. The authors show that the prefrontal cortex controls this type of memory organization in the hippocampus through direct projections to the medial entorhinal cortex.]]> André F. de SousaZachary E. ZeidlerDaniel G. Almeida-FilhoYang ShenAlessandro LuchettiShana SimanianMouaz MardiniLaura A. DeNardoAlcino J. Silva doi:10.1038/s41593-026-02231-1 Nature Neuroscience, Published online: 2026-04-28; | doi:10.1038/s41593-026-02231-1 2026-04-28 Nature Neuroscience 10.1038/s41593-026-02231-1 https://www.nature.com/articles/s41593-026-02231-1 https://www.nature.com/articles/s41593-026-02253-9 Nature Neuroscience, Published online: 28 April 2026; doi:10.1038/s41593-026-02253-9

The authors investigate the transcriptomic and connectivity organization of the basal ganglia and parafascicular nucleus. The analyses suggest that combinatorial gene expression underlies the modular and cell-type-specific basal ganglia input–output networks.]]> Quanxin WangAshwin BhandiwadNathan W. GouwensShenqin YaoYun WangXiuli KuangAnan LiXiangning LiRachel DalleyHsien-Chi KuoPhil LesnarWenjie XuMatt MalloryYaoyao LiLaila El-HifnawiLeila AhmadiniaBen OuelletteLauren KruseLydia NgHui GongQingming LuoMichael KunstCindy T. J. van VelthovenZizhen YaoStaci A. SorensenHongkui Zeng doi:10.1038/s41593-026-02253-9 Nature Neuroscience, Published online: 2026-04-28; | doi:10.1038/s41593-026-02253-9 2026-04-28 Nature Neuroscience 10.1038/s41593-026-02253-9 https://www.nature.com/articles/s41593-026-02253-9 https://www.nature.com/articles/s41593-026-02279-z Nature Neuroscience, Published online: 27 April 2026; doi:10.1038/s41593-026-02279-z

Using two-photon imaging in mice, Garborg et al. show that brain movement within the skull is driven by abdominal muscle contractions through mechanical coupling with the abdomen. Simulations suggest that this brain motion could contribute to cerebrospinal fluid circulation.]]> C. Spencer GarborgBeatrice GhittiQingguang ZhangJoseph M. RicottaNoah FrankSara J. MuellerDenver I. GreenawaltKevin L. TurnerRavi T. KedarasettiMarceline MostafaHyunseok LeeFrancesco CostanzoPatrick J. Drew doi:10.1038/s41593-026-02279-z Nature Neuroscience, Published online: 2026-04-27; | doi:10.1038/s41593-026-02279-z 2026-04-27 Nature Neuroscience 10.1038/s41593-026-02279-z https://www.nature.com/articles/s41593-026-02279-z https://www.nature.com/articles/s41593-026-02262-8 Nature Neuroscience, Published online: 27 April 2026; doi:10.1038/s41593-026-02262-8

The authors developed Cheese3D, a hardware–software framework for precise and sensitive measurement of whole-face movements in mice that enables quantitative inference of neural and physiological processes.]]> Kyle DaruwallaIrene Nozal MartinLinghua ZhangDiana NagličAndrew FrankelCatherine RasgaitisRubin ZhaoXinyan ZhangZainab AhmadJeremy C. BornigerXun Helen Hou doi:10.1038/s41593-026-02262-8 Nature Neuroscience, Published online: 2026-04-27; | doi:10.1038/s41593-026-02262-8 2026-04-27 Nature Neuroscience 10.1038/s41593-026-02262-8 https://www.nature.com/articles/s41593-026-02262-8 https://www.nature.com/articles/s41593-026-02312-1 Nature Neuroscience, Published online: 24 April 2026; doi:10.1038/s41593-026-02312-1

Author Correction: Astrocytic Sox9 overexpression in Alzheimer’s disease mouse models promotes Aβ plaque phagocytosis and preserves cognitive function]]> Dong-Joo ChoiSanjana MuraliWookbong KwonJunsung WooEun-Ah Christine SongYeunjung KoDebosmita SardarBrittney LozziYi-Ting ChengMichael R. WilliamsonTeng-Wei HuangKaitlyn SanchezJoanna JankowskyBenjamin Deneen doi:10.1038/s41593-026-02312-1 Nature Neuroscience, Published online: 2026-04-24; | doi:10.1038/s41593-026-02312-1 2026-04-24 Nature Neuroscience 10.1038/s41593-026-02312-1 https://www.nature.com/articles/s41593-026-02312-1