Nature Neuroscience provides the international neuroscience community with a highly visible forum in which the most exciting developments in all areas of neuroscience can be communicated to a broad readership. A lively front half, including News & Views, Reviews, Perspectives and editorials, helps place the primary research in context, providing readers with a broad perspective on the entire field. Nature Neuroscience aims to provide readers with authoritative, accessible and timely information on the most important advances in understanding the nervous system. Areas covered include molecular, cellular, systems, behavioral, cognitive and computational studies. http://feeds.nature.com/neuro/rss/current Nature Publishing Group en © 2026 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Nature Neuroscience © 2026 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. permissions@nature.com https://www.nature.com/uploads/product/neuro/rss.gif http://feeds.nature.com/neuro/rss/current https://www.nature.com/articles/s41593-026-02398-7 Nature Neuroscience, Published online: 13 August 2026; doi:10.1038/s41593-026-02398-7

STARFISH, a method for visualizing endogenous mRNA translation, is used to show that tau is translated exclusively in neuronal dendrites and rapidly degraded by neuroproteasomes. Failure of this degradation leads to accumulation of tau aggregates.]]> Kalin D. Konrad-VicarioVictoria ParadiseLara Y. DemirChi NguyenChristopher D. MakinsonZhao MingKapil V. Ramachandran doi:10.1038/s41593-026-02398-7 Nature Neuroscience, Published online: 2026-08-13; | doi:10.1038/s41593-026-02398-7 2026-08-13 Nature Neuroscience 10.1038/s41593-026-02398-7 https://www.nature.com/articles/s41593-026-02398-7 https://www.nature.com/articles/s41593-026-02403-z Nature Neuroscience, Published online: 12 August 2026; doi:10.1038/s41593-026-02403-z

The authors show that human neurons in bilateral corticolimbic sites fire together, modulated by working memory, and reinstate stimulus-selective firings when both sites briefly oscillate at 90 Hz, suggesting a mechanism for long-distance integration.]]> Ilya A. VerzhbinskyJonathan DaumeSophia ChengUeli RutishauserEric Halgren doi:10.1038/s41593-026-02403-z Nature Neuroscience, Published online: 2026-08-12; | doi:10.1038/s41593-026-02403-z 2026-08-12 Nature Neuroscience 10.1038/s41593-026-02403-z https://www.nature.com/articles/s41593-026-02403-z https://www.nature.com/articles/s41593-026-02416-8 Nature Neuroscience, Published online: 11 August 2026; doi:10.1038/s41593-026-02416-8

On 11 July 2026, neuroscience lost one of its most visionary scientists with the passing of Susumu Tonegawa at the age of 86. Across an extraordinary career spanning more than five decades, Tonegawa pursued biology’s deepest mysteries with relentless curiosity and unwavering conviction, inspiring generations of scientists to keep asking the hardest questions.]]> Steve Ramirez doi:10.1038/s41593-026-02416-8 Nature Neuroscience, Published online: 2026-08-11; | doi:10.1038/s41593-026-02416-8 2026-08-11 Nature Neuroscience 10.1038/s41593-026-02416-8 https://www.nature.com/articles/s41593-026-02416-8 https://www.nature.com/articles/s41593-026-02400-2 Nature Neuroscience, Published online: 11 August 2026; doi:10.1038/s41593-026-02400-2

Using cerebroids, a 3D ex vivo model of the human fetal brain, the authors show that IL-17A, a mediator of maternal immune activation linked to neurodevelopmental disorders, disrupts early human cortical development through NF-κB signaling.]]> Muhammad Z. K. AssirMario YanakievDo Hyeon GimSara S. M. ValkilaPaola MuscolinoPeng LiuLaetitia L. LecantePaul A. FowlerDaniel A. BergEunchai Kang doi:10.1038/s41593-026-02400-2 Nature Neuroscience, Published online: 2026-08-11; | doi:10.1038/s41593-026-02400-2 2026-08-11 Nature Neuroscience 10.1038/s41593-026-02400-2 https://www.nature.com/articles/s41593-026-02400-2 https://www.nature.com/articles/s41593-026-02392-z Nature Neuroscience, Published online: 07 August 2026; doi:10.1038/s41593-026-02392-z

Endocannabinoid-dependent corticostriatal plasticity underlies avoidance learning in mice after a single experience. Disrupting this process impairs learning, revealing a nonclassical synaptic basis supporting one-shot learning.]]> Charlotte PietteArnaud HubertSylvie PerezJérémy PeixotoNicolas GervasiHugues BerryJonathan TouboulLaurent Venance doi:10.1038/s41593-026-02392-z Nature Neuroscience, Published online: 2026-08-07; | doi:10.1038/s41593-026-02392-z 2026-08-07 Nature Neuroscience 10.1038/s41593-026-02392-z https://www.nature.com/articles/s41593-026-02392-z https://www.nature.com/articles/s41593-026-02391-0 Nature Neuroscience, Published online: 07 August 2026; doi:10.1038/s41593-026-02391-0

A multimodal cell-type atlas of the mouse insular cortex reveals specialized pyramidal types and circuits in distinct insular subregions, as well as intra-insular functional connections that integrate sensory inputs with valence.]]> Bart C. JongbloetsYang ChenMichael A. MuniakIan K. GingerichKayla A. MaanumTianyi Mao doi:10.1038/s41593-026-02391-0 Nature Neuroscience, Published online: 2026-08-07; | doi:10.1038/s41593-026-02391-0 2026-08-07 Nature Neuroscience 10.1038/s41593-026-02391-0 https://www.nature.com/articles/s41593-026-02391-0 https://www.nature.com/articles/s41593-026-02380-3 Nature Neuroscience, Published online: 06 August 2026; doi:10.1038/s41593-026-02380-3

Charbonneau et al. compare how the insula is structured and functions in humans, monkeys and rodents, revealing similarities and differences across species that are likely to impact the translation of animal research to humans.]]> Joey A. CharbonneauSarah B. CarpJeffrey L. BennettSavannah M. MawGilda MoadabJohn P. ChristiansonMark G. BaxterEliza Bliss-Moreau doi:10.1038/s41593-026-02380-3 Nature Neuroscience, Published online: 2026-08-06; | doi:10.1038/s41593-026-02380-3 2026-08-06 Nature Neuroscience 10.1038/s41593-026-02380-3 https://www.nature.com/articles/s41593-026-02380-3 https://www.nature.com/articles/s41593-026-02397-8 Nature Neuroscience, Published online: 06 August 2026; doi:10.1038/s41593-026-02397-8

This study finds that shed NLGN3 interacts with the glycosylated surface protein CSPG4 on both normal and malignant glial cells, activating mechanotransduction pathways that drive glioma growth and maintain oligodendroglial progenitor states.]]> Yoon Seok KimShawn M. GillespieAnna C. GeraghtyBelgin YalçınAlexis English IvecAerin YangRebecca MancusiJared HysingerJames ReedRichard DrexlerMichael QuezadaKaren MalaconPamelyn WooYoukyeong Gloria ByunChristopher MountMable LamYuan PanJ. Bradley ZucheroJacqueline TrotterMichelle Monje doi:10.1038/s41593-026-02397-8 Nature Neuroscience, Published online: 2026-08-06; | doi:10.1038/s41593-026-02397-8 2026-08-06 Nature Neuroscience 10.1038/s41593-026-02397-8 https://www.nature.com/articles/s41593-026-02397-8